Most rich people enjoy playing God to an extent. I think when you claim absolute knowledge you don't really have a very good argument though. I have no issues with people wishing him to fail at his ventures though. I think it is bad character to wish him to fail personally. It has little to do with whether you agree or disagree with his philosophies.
Soros is an evil SOB. If he had his way, you and I would suffer intensely. He's not just a rich man pretending to play God. He's an uber rich man that can actually pull some of it off. There are nations that have never recovered from his meddling. America, by his own admission, is the main goal of these types. Yes, I wish he would kill off. The nation will be a bit safer.